Post-traumatic Stress Disorder – PTSD


Ketamine Infusion Treatment for Post-traumatic Stress Disorder – PTSD

Ketamine and PTSD

The National Institute of Mental Health defines Post-traumatic Stress Disorder (PTSD) as “a disorder that develops in some people who have experienced a shocking, scary, or dangerous event”. The more extensive definition of PTSD, as per the Diagnostic and Statistical Manual of Mental Disorders-5, can be found here. PTSD symptoms can include but are not limited to nightmares, flashbacks, frightening thoughts, hyperarousal, and avoidance of anything or anyone that serves as a reminder of the event. Symptoms usually show up within 3 months following the traumatizing event but can also begin years afterward. PTSD symptoms can disrupt a person’s life, interfering with his ability to maintain relationships and employment.


What You Can Expect

In 2008, The Journal of TRAUMA Injury, Infection, and Critical Care published research that suggested a correlation between ketamine and PTSD in burned service members. The researchers looked retrospectively at medications that were used in surgical procedures of burned service members, and they measured their PTSD symptoms. One hundred nineteen (119) soldiers had received low doses of ketamine during surgery, while 28 did not receive ketamine. The prevalence of PTSD was significantly lower for the soldiers who had received perioperative ketamine than for those who did not receive ketamine.


We Offer

Northern Michigan Ketamine and Wellness is now offering ketamine infusion therapy for patients who have been diagnosed with PTSD and who have not found relief from their current treatment regimen. Our treatment protocol for PTSD is as follows: 2 infusions per week, over the course of 4 weeks. Within this time frame, our team will work with you to monitor the efficacy of the treatment, provide you with support, and collaborate with your primary mental health provider to assist you in meeting your goals. Following your initial treatment, a member of our staff will follow up with you and your primary mental health provider to monitor your depressive symptoms and determine your need for maintenance infusions.

Contact Us



Once you contact us and/or we receive a referral from your primary mental health provider i.e., psychiatrist, psychologist, social worker, or counselor you will be contacted by our team. You will receive a NMKW initial screening packet to complete and return for our physicians to determine if you are a candidate for ketamine therapy. If so, you will be contacted to schedule your clinical interview and potential infusion date. NMKW offers ketamine infusions in a quiet, spa-like environment with safety and precision provided by a board-certified anesthesiologist. Wear comfortable clothing as you simply recline in a chair during your treatments. You have the option to rest quietly or listen to soft music. Plan to be here for about 2 hours when you scheduled for an infusion. Infusions take anywhere from 45-60 minutes with a 30 minute after-infusion observance period.


Our goal at NMKW is to offer adjunct therapy to the treatment you are already providing your patient. We want to collaborate with you to provide ketamine therapy for your patients with PTSD. Our screening protocols include medical history assessment, PCL-5 score tracking, and depression/addiction screening if indicated. As part of this screening process, clarification of past treatments and responses will be obtained. Once clinical appropriateness is determined, ketamine infusion therapy will involve a sub-anesthetic and sub-dissociative dose given slowly, monitored by a board certified anesthesiologist, built around best practices. To initiate treatment for your patient we will need patient contact information as well as pertinent medical records. To refer your patient to NMKW contact us at 989-350-9155. We are also considering offering a series of ultrasound-guided stellate ganglion blocks in conjunction with ketamine therapy.


Here’s some research you might find helpful

American Medical Association


Neurobiology of Disease



  • What is Ketamine?

    Ketamine, a derivative of phencyclidine, is an anesthetic drug that was developed in 1962 and has been widely used in a variety of settings. Ketamine acts as an antagonist of the N-methyl-D-aspartate (NMDA) receptor and targets glutamate, which is an excitatory amino acid neurotransmitter. Ketamine has been used to induce and maintain general anesthesia for more than 30years and is on the World Health Organizations List of Essential Medicines. Ketamine is FDA-approved as an anesthetic and has a remarkably safe track record in clinical settings.

  • How long does it last?

    The duration of symptomatic relief patients experience following ketamine therapy varies greatly. After finishing the first series of infusions we will follow your length of relief. Patients who have return of symptoms may receive maintenance or "tune up" infusions to extend their response. When patients do experience such relief, it may be the first time in years that they have felt healthy and "normal".

  • Why haven't I heard of this before?

    Ketamine is most commonly known as an anesthetic used in surgical procedures. You may know of ketamine as a rave drug used recreationally since the 1980's. The utilization of ketamine to treat PTSD is not yet FDA-approved, as the approval process can take years due to funding, research and time required.

  • Is it safe?

    When ketamine is administered in a controlled medical setting by a properly trained and licensed clinician using established methods, monitoring, and protocols it is very safe. When used recreationally ketamine use can have very serious adverse effects.

  • What are the side effects?

    Most research shows some possible short-lived side effects including headache, anxiety, dissociation, nausea, and dizziness. 

    These can be commonly treated on site.

  • Is it legal?

    Yes, this is legal. Ketamine treatment is an intravenous infusion performed in a specially-equipped medical office under the direction of a physician.

  • Is this treatment covered by insurance?

    No, not yet. NMKW accepts payments via money order, cash,or credit card.


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